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Interventional Pulmonology

Lung cancer is the world’s leading cause of cancer deaths, and is largely preventable

Lung cancer is responsible for 1 in 5 cancer deaths and largely preventable.1,2 Biopsy diagnostic yield using current standards of care varies from 46% to 88% in advanced bronchoscope techniques, and complications due to lung biopsies are associated with morbidity risk.3,4

Reach better diagnosis for your bronchoscopy procedure with Cellvizio® 

Physicians have been using Cellvizio® to image lung tissue from proximal airways down to alveoli in patients presenting pulmonary lesions.
In the context of pulmonary lesions, live unlimited tissue assessment can assist the physician or surgeon in :

  • Targeting and confirming that the area of interest for 
    histological sampling is reached5,6
  • Visualizing immediately abnormal tissues5-9

Normal Lung Alveoli

"Compact Alveoli" pattern assisted cancer detection with sensitivities ranging from 70% to 80%2

Normal Lung Bronchi

CLE may lead to an optimized rapid in vivo diagnosis of neoplastic changes in patients with suspected lung cancer

Dr. Florian Fuchs 

University Hospital Erlangen, Germany


1. The American Cancer Society medical and editorial content team, Key statistics for Lung Cancer, 2019.
2. Lung Cancer, American Cancer Society, http://canceratlas.cancer.org/the-burden/lung-cancer/, Accessed May 31 2019.
3. Ost D.E. et al. Diagnostic Yield and Complications of Bronchoscopy for Peripheral Lung Lesions. Results of the AQuIRE Registry. Am J Respir Crit Care Med, 2017.
4. Carol C. Wu. et al. Complications of CT-Guided Percutaneous Needle Biopsy of the Chest: Prevention and Management, American Journal of Roentgenology, 2011.
5. Thiberville L. et al. Human in vivo fluorescence microimaging of the alveolar ducts and sacs during bronchoscopy. European Respiratory Journal, 2009.
6. Arenberg DA, Gildea T, Wilson D. Proposed Classification Of Probe-Based Confocal Laser Endomicroscopy (pCLE) Findings For Evaluation Of Indeterminate Peripheral Lung Nodules. American Journal of Respiratory and Critical Care, 2011.
7. Fuchs F.S et al. Confocal Laser Endomicroscopy for diagnosing Lung Cancer in vivo. European Respiratory Journal, 2012.
8. Shulimzon TR. et al. Real-time vision of a sarcoid granuloma at bronchoscopy. American Journal of Respiratory and Critical Care, 2013.
9. Yserbyt J. et al. Perspectives using probe-based confocal laser endomicroscopy of the respiratory tract. Swiss Medical Weekly, 2013.

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