{"id":9123,"date":"2024-08-07T11:18:02","date_gmt":"2024-08-07T09:18:02","guid":{"rendered":"https:\/\/www.maunakeatech.com\/indications\/gastroenterology\/inflammatory-bowel-diseases-us\/"},"modified":"2024-12-30T08:41:19","modified_gmt":"2024-12-30T07:41:19","slug":"inflammatory-bowel-diseases","status":"publish","type":"page","link":"https:\/\/www.maunakeatech.com\/int\/indications\/gastroenterology\/inflammatory-bowel-diseases\/","title":{"rendered":"Inflammatory Bowel Diseases"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.25.1″ _module_preset=”default” background_image=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/AdobeStock_812003556_Preview.jpg” custom_margin=”||||false|false” custom_padding=”80px||100px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.25.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text disabled_on=”on|off|off” _builder_version=”4.27.0″ _module_preset=”default” text_font=”|–et_global_heading_font_weight|||||||” text_text_color=”#FF6720″ header_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_text_color=”#FFFFFF” header_font_size=”50px” header_line_height=”1.1em” custom_margin=”20px||20px||true|false” header_font_size_tablet=”50px” header_font_size_phone=”45px” header_font_size_last_edited=”on|phone” saved_tabs=”all” locked=”off” global_colors_info=”{}”]<\/p>\n

Inflammatory Bowel Diseases<\/h1>\n

[\/et_pb_text][et_pb_text disabled_on=”off|on|on” _builder_version=”4.27.0″ _module_preset=”default” text_font=”|–et_global_heading_font_weight|||||||” text_text_color=”#FF6720″ header_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_text_color=”#FFFFFF” header_font_size=”50px” header_line_height=”1.1em” header_2_text_color=”#FAFAFA” custom_margin=”20px||20px||true|false” header_font_size_tablet=”50px” header_font_size_phone=”45px” header_font_size_last_edited=”on|phone” saved_tabs=”all” locked=”off” global_colors_info=”{}”]<\/p>\n

Inflammatory Bowel Diseases<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_font=”–et_global_heading_font|300|||||||” text_text_color=”#FFFFFF” text_font_size=”22px” text_line_height=”1.2em” locked=”off” global_colors_info=”{}”]<\/p>\n

Cellvizio\u00ae<\/sup> is the real-time in vivo cellular imaging platform that allows you to observe, understand, and predict relapse and remission cycles while managing Inflammatory Bowel Disease. (IBD)<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.25.2″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” min_height=”507.4px” custom_margin=”||-40px|||” da_disable_devices=”off|off|off” locked=”off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” _builder_version=”4.25.2″ _module_preset=”default” locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.1″ _module_preset=”default” background_color=”#092840″ custom_padding=”40px|40px|40px|40px|false|true” custom_css_main_element=”min-height:250px; display: flex;|| flex-direction: column;|| justify-content: center;||||\/* Et les d\u00e9clinaisons avec pr\u00e9fixes pour obtenir un r\u00e9sultat homog\u00e8ne sur les divers navigateurs *\/|| display: -webkit-box;|| display: -webkit-flex;|| display: -moz-box;|| display: -ms-flexbox;|| -webkit-box-orient: vertical;|| -webkit-box-direction: normal;|| -webkit-flex-direction: column;|| -moz-box-orient: vertical;|| -moz-box-direction: normal;|| -ms-flex-direction: column;|| -webkit-box-pack: center;|| -webkit-justify-content: center;|| -moz-box-pack: center;|| -ms-flex-pack: center;||}” pac_dcm_carousel_specific_module_num=”0″ border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_font=”–et_global_body_font|300|||||||” text_text_color=”#FFFFFF” text_font_size=”22px” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

Under current protocol, 30% of IBD patients relapse every year 1,2<\/sup><\/span><\/b><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.25.1″ _module_preset=”default” custom_margin=”20px||||false|false” locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_text_color=”#FAFAFA” text_font_size=”18px” locked=”off” global_colors_info=”{}”]<\/p>\n

52% of Ulcerative Colitis (UC) patients who have an active disease are included in this statistic.1<\/sup>\u00a0As a result,\u00a0187,000 hospitalizations<\/b>\u00a0per year, take place, specifically for Crohn’s disease (CD) in the US.3<\/sup>\u00a0Current disease assessment techniques are suboptimal and do not accurately predict long term prognosis.4<\/sup><\/span><\/p>\n

Cellvizio enables you to determine the optimal course of action for IBD with the knowledge of point-in-time reactions as they happen in real-time.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.27.0″ _module_preset=”default” background_color=”#092840″ z_index=”0″ custom_padding=”80px||280px||false|false” custom_padding_tablet=”80px||280px||false|false” custom_padding_phone=”80px||||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”4″ make_equal=”on” _builder_version=”4.27.0″ _module_preset=”default” background_enable_color=”off” custom_padding=”30px|1px|30px|1px|true|true” custom_css_main_element=”align-items:center;” locked=”off” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.25.0″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_divider color=”#FF6720″ divider_weight=”7px” _builder_version=”4.25.0″ _module_preset=”default” background_enable_color=”off” width=”94px” custom_margin=”||0px||false|false” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” header_2_font=”|–et_global_heading_font_weight|||||||” header_2_text_color=”#FAFAFA” header_2_font_size=”40px” custom_margin=”||||false|false” global_colors_info=”{}”]<\/p>\n

Cellvizio\u00ae<\/sup> Clinical Value<\/h2>\n

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With Cellvizio\u00ae<\/sup> physicians predict relapse within the next 12 months, as well as major clinical events that require hospitalization or surgery for IBD patients.5,6<\/sup>
It also allows identification of residual colonic inflammation not detectable macroscopically in patients with IBD which in turn can help in determining the need for additional anti-inflammatory therapy and allows prediction of clinical outcomes.12<\/sup>
As a result, physicians are\u00a0able to monitor treatment to differentiate responders from non-responders for UC patients.7<\/sup><\/p>\n

[\/et_pb_text][et_pb_button button_url=”\/landing-pages\/gi-publication\/” url_new_window=”on” button_text=”Download our GI Publication Summary” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”70px||-6px||false|false” custom_margin_tablet=”50px||||false|false” custom_margin_phone=”||40px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”9px|40px|9px|40px|true|true” hover_enabled=”0″ locked=”off” global_colors_info=”{}” sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.25.0″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ border_radii=”on|30px|30px|30px|30px” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/11\/inflammatory-bowel-diseases-1-1.png” title_text=”inflammatory bowel diseases” align=”center” _builder_version=”4.27.0″ _module_preset=”default” module_alignment=”center” custom_css_free_form=”\/* Hide image titles on hover *\/||img {||pointer-events:none;||}” border_radii=”on|30px|30px|30px|30px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.27.0″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” custom_padding=”0px||140px||false|false” custom_padding_tablet=”0px||140px||false|false” custom_padding_phone=”0px||60px||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.27.0″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” width=”40%” width_tablet=”40%” width_phone=”80%” width_last_edited=”on|phone” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”-220px||||false|false” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_image src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/logo-1.jpg” title_text=”logo” align=”center” _builder_version=”4.27.0″ _module_preset=”default” background_enable_color=”off” width=”18%” width_tablet=”18%” width_phone=”40%” width_last_edited=”on|phone” module_alignment=”center” custom_margin=”||20px||false|false” custom_padding=”||||false|false” border_radii=”on|80px|80px|80px|80px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.0″ _module_preset=”default” background_color=”#FFFFFF” width=”40%” width_tablet=”40%” width_phone=”80%” width_last_edited=”on|phone” custom_margin=”-110px||||false|false” custom_padding=”80px||70px||false|false” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.2″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_font_size=”18px” background_color=”RGBA(255,255,255,0)” text_orientation=”center” custom_padding=”|50px||50px|false|true” border_radii=”off|30px|30px||” locked=”off” global_colors_info=”{}”]<\/p>\n

“Cellvizio\u00ae<\/sup><\/span> is the only technology that allows us to see functional healing, and it is worth having this information as it is the best determinant of outcome for my IBD patients”<\/p>\n

[\/et_pb_text][et_pb_blurb title=”Prof. Dr. T. Rath” icon_alignment=”left” _builder_version=”4.27.0″ _module_preset=”default” header_level=”h6″ header_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_text_color=”#41B6E6″ background_color=”RGBA(255,255,255,0)” text_orientation=”center” custom_margin=”30px||||false|false” border_radii=”off|||30px|30px” border_radii_image=”on|30px|30px|30px|30px” locked=”off” global_colors_info=”{}”]<\/p>\n

University Hospital Erlangen<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.25.2″ _module_preset=”default” background_color=”#071621″ background_image=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/AdobeStock_834769802_Preview-2.jpg” parallax=”on” parallax_method=”off” da_disable_devices=”off|off|off” locked=”off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.0″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_divider color=”#FF6720″ divider_weight=”7px” _builder_version=”4.25.0″ _module_preset=”default” background_enable_color=”off” width=”94px” custom_margin=”||0px||false|false” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.25.1″ _module_preset=”default” header_2_font=”|–et_global_heading_font_weight|||||||” header_2_text_color=”#FAFAFA” header_2_font_size=”40px” global_colors_info=”{}”]<\/p>\n

Patient Management<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ make_equal=”on” _builder_version=”4.27.0″ _module_preset=”default” background_color=”#092840″ width_tablet=”” width_phone=”90%” width_last_edited=”on|phone” custom_margin=”20px||||false|false” custom_padding=”50px|40px|50px|40px|true|true” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][et_pb_column type=”3_5″ module_class=”centrer-vertical” _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_text_color=”#FAFAFA” text_font_size=”18px” locked=”off” global_colors_info=”{}”]<\/p>\n

With Cellvizio\u00ae<\/sup>, patient management is improved because physicians can now differentiate between diagnoses of IBD (92% sensitivity, 91% specificity).<\/span>8<\/sup>\u00a0They can also predict relapse and enable tailored biologic therapy to reduce IBD-related hospitalizations.<\/span>9\u00a0<\/span><\/sup>During a flare period, mucosal inflammation is confirmed.<\/span>10\u00a0<\/sup>The treatment improves\u00a0because physicians can assess mucosal barrier function for predicting improved long-term patient outcomes for UC patients.<\/span>7\u00a0<\/sup>Furthermore, CLE barrier healing was highly accurate for predicting the further course of disease and exceeded endoscopic and histologic remission for predicting a survival free of major adverse outcomes.<\/span>13<\/sup>\u00a0In the case of cancer, physicians improve care by being able to characterize suspicious lesions.<\/span>11<\/sup><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_image src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/inflammatory-bowel-diseases-2.png” title_text=”inflammatory-bowel-diseases-2″ _builder_version=”4.27.0″ _module_preset=”default” custom_margin=”||51px|||” custom_margin_tablet=”||51px|||” custom_margin_phone=”||0px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”||36px|||” custom_css_free_form=”\/* Hide image titles on hover *\/||img {||pointer-events:none;||}” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.25.1″ _module_preset=”default” background_color=”#071621″ da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.25.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.0″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_divider color=”#FF6720″ divider_weight=”7px” _builder_version=”4.25.1″ _module_preset=”default” background_enable_color=”off” width=”94px” module_alignment=”left” custom_margin=”||0px||false|false” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text disabled_on=”on|off|off” _builder_version=”4.27.0″ _module_preset=”default” header_2_font=”|–et_global_heading_font_weight|||||||” header_2_text_align=”left” header_2_text_color=”#FAFAFA” header_2_font_size=”40px” global_colors_info=”{}”]<\/p>\n

Cellvizio\u00ae<\/sup> mucosal assessment
<\/span><\/span><\/h2>\n

using <\/span><\/span>Cellvizio\u00ae <\/sup>ColoFlexTM\u00a0<\/sup>UHD Miniprobe\u00a0<\/span><\/span><\/h2>\n

[\/et_pb_text][et_pb_text disabled_on=”off|on|on” _builder_version=”4.27.0″ _module_preset=”default” header_2_font=”|–et_global_heading_font_weight|||||||” header_2_text_align=”left” header_2_text_color=”#FAFAFA” header_2_font_size=”40px” header_3_text_color=”#FAFAFA” global_colors_info=”{}”]<\/p>\n

Cellvizio\u00ae<\/sup> mucosal <\/span><\/span><\/h3>\n

assessment <\/span><\/span>using <\/span><\/span><\/h3>\n

<\/h3>\n

Cellvizio\u00ae <\/sup>ColoFlexTM\u00a0<\/sup><\/span><\/span><\/h3>\n

UHD Miniprobe\u00a0<\/span><\/span><\/h3>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ custom_padding_last_edited=”on|phone” _builder_version=”4.27.0″ _module_preset=”default” background_color=”#092840″ width_tablet=”” width_phone=”90%” width_last_edited=”on|phone” max_width=”1200px” custom_margin=”40px||||false|false” custom_padding=”50px|70px|50px|70px|true|true” custom_padding_tablet=”50px|70px|50px|70px|true|true” custom_padding_phone=”50px|30px|50px|30px|true|true” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” header_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_text_color=”#FFFFFF” header_3_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_3_text_align=”center” header_3_text_color=”#FFFFFF” custom_margin=”||15px||false|false” locked=”off” global_colors_info=”{}”]<\/p>\n

Healthy Mucosa<\/h3>\n

[\/et_pb_text][et_pb_divider color=”#FF6720″ divider_weight=”4px” _builder_version=”4.25.1″ _module_preset=”default” background_enable_color=”off” width=”60px” module_alignment=”center” custom_margin=”||0px||false|false” custom_css_main_element=”margin-left: auto;||margin-right: auto;” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_text_color=”#FAFAFA” text_orientation=”center” min_height=”110px” min_height_tablet=”110px” min_height_phone=”110px” min_height_last_edited=”on|phone” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n

Criteria: dark goblet cells, regular and narrow vessels surrounding crypts and round crypt structures<\/span><\/p>\n

[\/et_pb_text][et_pb_video src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/healthy-mucosa.mp4″ image_src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/healthy-mucosa.png” _builder_version=”4.27.0″ _module_preset=”default” custom_margin=”145px||||false|false” custom_margin_tablet=”50px||||false|false” custom_margin_phone=”30px||50px||false|false” custom_margin_last_edited=”on|phone” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][\/et_pb_video][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” header_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_text_color=”#FFFFFF” header_3_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_3_text_align=”center” header_3_text_color=”#FFFFFF” custom_margin=”||15px||false|false” locked=”off” global_colors_info=”{}”]<\/p>\n

Ulcerative colitis<\/h3>\n

[\/et_pb_text][et_pb_divider color=”#FF6720″ divider_weight=”4px” _builder_version=”4.25.1″ _module_preset=”default” background_enable_color=”off” width=”60px” module_alignment=”center” custom_margin=”||0px||false|false” custom_css_main_element=”margin-left: auto;||margin-right: auto;” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_text_color=”#FAFAFA” text_orientation=”center” min_height=”110px” min_height_tablet=”110px” min_height_phone=”110px” min_height_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

Criteria: mild to moderate increase of capillaries, dilated and distorted capillaries<\/span><\/p>\n

[\/et_pb_text][et_pb_video src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/ulcerative-colitis.mp4″ image_src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/ulcerative-colitis.png” _builder_version=”4.27.0″ _module_preset=”default” custom_margin=”101px||||false|false” custom_margin_tablet=”50px||50px||false|false” custom_margin_phone=”30px||50px||false|false” custom_margin_last_edited=”on|phone” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][\/et_pb_video][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” header_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_text_color=”#FFFFFF” header_3_font=”–et_global_heading_font|–et_global_heading_font_weight|||||||” header_3_text_align=”center” header_3_text_color=”#FFFFFF” custom_margin=”||15px||false|false” locked=”off” global_colors_info=”{}”]<\/p>\n

Dysplastic Mucosa<\/h3>\n

[\/et_pb_text][et_pb_divider color=”#FF6720″ divider_weight=”4px” _builder_version=”4.25.1″ _module_preset=”default” background_enable_color=”off” width=”60px” module_alignment=”center” custom_margin=”||0px||false|false” custom_css_main_element=”margin-left: auto;||margin-right: auto;” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.27.0″ _module_preset=”default” text_text_color=”#FAFAFA” text_orientation=”center” min_height=”110px” min_height_tablet=”110px” min_height_phone=”110px” min_height_last_edited=”on|phone” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n

Criteria: ridged-lined irregular epithelial layer with loss of crypts and goblet cells,\u00a0Irregular cell architecture with little or no mucin<\/span><\/p>\n

[\/et_pb_text][et_pb_video src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/dysplastic-mucosa.mp4″ image_src=”https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/dysplastic-mucosa.png” _builder_version=”4.27.0″ _module_preset=”default” custom_margin=”50px||||false|false” custom_margin_tablet=”50px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|phone” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{}”][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.27.0″ _module_preset=”default” background_color=”#092840″ custom_padding_tablet=”” custom_padding_phone=”30px||30px||true|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.25.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.25.1″ _module_preset=”default” pac_dcm_carousel_specific_module_num=”0″ global_colors_info=”{}”][et_pb_toggle title=”References & disclaimers” open_toggle_text_color=”#FFFFFF” open_toggle_background_color=”#071621″ closed_toggle_text_color=”#FFFFFF” closed_toggle_background_color=”#071621″ icon_color=”#FFFFFF” toggle_icon=”3||divi||400″ use_icon_font_size=”on” icon_font_size=”36px” open_icon_color=”#FFFFFF” open_toggle_icon=”2||divi||400″ open_use_icon_font_size=”on” open_icon_font_size=”36px” _builder_version=”4.27.0″ _module_preset=”default” title_font=”|700|||||||” title_font_size=”18px” closed_title_font=”|600|||||||” body_text_color=”#FFFFFF” body_font_size=”14px” custom_margin=”||||false|false” custom_padding=”30px|40px|30px|40px|true|true” custom_css_free_form=”selector .et_pb_toggle_content li {|| padding-bottom:8px;||}||selector .et_pb_toggle_content li:marker {|| font-weight:700;||}” border_radii=”on|15px|15px|15px|15px” border_width_all=”0px” global_colors_info=”{}”]<\/p>\n

    \n
  1. Data from Crohn\u2019s & Colitis Foundation of America, 2014. https:\/\/www.crohnscolitisfoundation.org\/sites\/default\/files\/2019-02\/Updated%20IBD%20Factbook.pdf.<\/li>\n
  2. Bitton A. et al. Predicting relapse in Crohn\u2019s disease: a biopsychosocial model. Gut, 2008.<\/li>\n
  3. CDC\/NCHS national hospital discharge survey: United States, 2010. Centers for Disease Control and Prevention website. www.cdc.gov\/nchs\/data\/nhds\/10Detaileddiagnosesprocedures\/2010det10_numberalldiagnoses.pdf<\/li>\n
  4. Liverani E. et al. How to predict clinical relapse in inflammatory bowel disease patients. World J Gastroenterol 2016<\/li>\n
  5. Turcotte JF. et al. Increased Epithelial Gaps in the Small Intestine Are Predictive of Hospitalization and Surgery in Patients With Inflammatory Bowel Disease, Clin tranfl Gastroenterol, 2012.<\/li>\n
  6. Tontini GE. et al. Prediction of clinical outcomes in Crohn\u2019s disease by using confocal laser endomicroscopy: results from a prospective multicenter study. Gastrointestinal Endoscopy. 2017.<\/li>\n
  7. Hundorfean G. et al. Development and Validation of a Confocal Laser Endomicroscopy-Based Score for In Vivo Assessment of Mucosal Healing in Ulcerative Colitis Patients. Inflamm Bowel Dis, 2017.<\/li>\n
  8. Queneherve L. et al. Quantitative assessment of mucosal architecture using computer-based analysis of confocal laser endomicroscopy in inflammatory bowel diseases. Gastrointest Endosc, (Epub), 2018.<\/li>\n
  9. Liu J. et al. Personalized Inflammatory Bowel Disease Care Reduced Hospitalizations. Digestive Diseases and Sciences, 2019.<\/li>\n
  10. Maione F. et al. Confocal laser endomicroscopy in ulcerative colitis: beyond endoscopic assessment of disease activity. Tech Coloproctol, (Epub), 2017.<\/li>\n
  11. Lord R. et al. Colonic lesion characterization in inflammatory bowel disease: A systematic review and metaanalysis. World J Gastroenterol, 2018.<\/li>\n
  12. Al-Mansour.\u00a0et al.\u00a0SAGES TAVAC safety and efficacy analysis confocal laser endomicroscopy.\u00a0Surg Endosc, 2020.<\/li>\n
  13. Rath T, et al. Intestinal Barrier Healing Is Superior to Endoscopic and Histologic Remission for Predicting Major Adverse Outcomes in Inflammatory Bowel Disease: The Prospective ERIca Trial. Gastroenterology, 2022.<\/li>\n<\/ol>\n

    <\/span><\/p>\n

    Cellvizio\u00ae<\/sup>\u00a0<\/span>I.V.E. with Confocal Miniprobes\u2122\u00a0are regulated Medical Devices, CE marked (CE 0459) (Class IIa – NB : G-MED) and FDA cleared. Cellvizio\u00ae<\/sup>\u00a0<\/span>is a registered trademark and Confocal Miniprobe\u2122 is a trademark of Mauna Kea Technologies. Cellvizio\u00ae<\/sup>\u00a0<\/span>I.V.E. with Confocal Miniprobes\u2122 is a confocal laser system with fiber optic probes that are intended to allow imaging of the internal microstructure of tissues including, but not limited to, the identification of cells and vessels and their organization or architecture. Once connected to the Cellvizio\u00ae<\/sup>\u00a0<\/span>I.V.E. system: The GastroFlex\u2122 UHD and ColoFlex\u2122 UHD Confocal Miniprobes\u2122 are intended to allow imaging of anatomical tracts, i.e., gastrointestinal systems, accessed by an endoscope or endoscopic accessories. Please consult labels and instructions for use. These statements and the associated reference to specific clinical studies, are not intended to represent claims of safety or effectiveness for detecting or treating any specific condition or disease state. Rather this information is intended to provide useful reference to selected published literature describing physician experiences with the associated clinical uses. Any diagnostic assessment should always be made by the attending physician, based on the evaluation of all sources of clinical, endoscopic and other relevant information. These statements have not been reviewed, cleared, or approved by the U.S. FDA. The use of this medical device is exclusively reserved for health professionals.\u00a0Product availability cannot be guaranteed in all countries. For further information, please contact your local sales representative.<\/p>\n

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    Inflammatory Bowel DiseasesInflammatory Bowel DiseasesCellvizio\u00ae is the real-time in vivo cellular imaging platform that allows you to observe, understand, and predict relapse and remission cycles while managing Inflammatory Bowel Disease. (IBD)Under current protocol, 30% of IBD patients relapse every year 1,252% of Ulcerative Colitis (UC) patients who have an active disease are included in this […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":8466,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-9123","page","type-page","status-publish","hentry"],"yoast_head":"\nInflammatory Bowel Diseases - Mauna Kea Technologies<\/title>\n<meta name=\"description\" content=\"Cellvizio\u00ae is the real-time in vivo cellular imaging platform that allows you to observe, understand, and predict relapse and remission cycles while managing Inflammatory Bowel Disease. 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