{"id":1183,"date":"2024-05-07T11:47:21","date_gmt":"2024-05-07T09:47:21","guid":{"rendered":"https:\/\/www.maunakeatech.com\/barretts-esophagus\/"},"modified":"2026-02-04T21:52:15","modified_gmt":"2026-02-04T20:52:15","slug":"barretts-esophagus","status":"publish","type":"page","link":"https:\/\/www.maunakeatech.com\/int\/indications\/gastroenterology\/barretts-esophagus\/","title":{"rendered":"Barrett\u2019s Esophagus"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_image=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/AdobeStock_812003556_Preview.jpg&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;80px||100px||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; text_text_color=&#8221;#FF6720&#8243; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;50px&#8221; header_line_height=&#8221;1.1em&#8221; custom_margin=&#8221;20px||20px||true|false&#8221; header_font_size_tablet=&#8221;50px&#8221; header_font_size_phone=&#8221;45px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>Barrett&#8217;s Esophagus<\/h1>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;&#8211;et_global_heading_font|300|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;22px&#8221; text_line_height=&#8221;1.2em&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Cellvizio<span><sup>\u00ae<\/sup><\/span> is the real-time in vivo cellular imaging platform that is an adjunct to the standard of care and enables physicians to detect and monitor the progression of GERD to Barrett\u2019s Esophagus (BE) over time using proprietary advanced imaging technology.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; da_disable_devices=&#8221;off|off|off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; custom_padding=&#8221;40px|40px|40px|40px|false|true&#8221; custom_css_main_element=&#8221;min-height:250px;  display: flex;||  flex-direction: column;||  justify-content: center;||||\/* Et les d\u00e9clinaisons avec pr\u00e9fixes pour obtenir un r\u00e9sultat homog\u00e8ne sur les divers navigateurs  *\/||  display: -webkit-box;||  display: -webkit-flex;||  display: -moz-box;||  display: -ms-flexbox;||  -webkit-box-orient: vertical;||  -webkit-box-direction: normal;||  -webkit-flex-direction: column;||     -moz-box-orient: vertical;||     -moz-box-direction: normal;||      -ms-flex-direction: column;||  -webkit-box-pack: center;||  -webkit-justify-content: center;||     -moz-box-pack: center;||      -ms-flex-pack: center;||}&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;&#8211;et_global_body_font|300|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;18px&#8221; text_orientation=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Esophageal cancer is the <strong>fastest growing cancer\u00b2&#8230;<\/strong><\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/barretts-picto1.png&#8221; title_text=&#8221;barretts-picto1&#8243; show_bottom_space=&#8221;off&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; width=&#8221;60%&#8221; custom_margin=&#8221;30px||||false|false&#8221; custom_padding=&#8221;||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; custom_padding=&#8221;40px|40px|40px|40px|false|true&#8221; custom_css_main_element=&#8221;min-height:250px;  display: flex;||  flex-direction: column;||  justify-content: center;||||\/* Et les d\u00e9clinaisons avec pr\u00e9fixes pour obtenir un r\u00e9sultat homog\u00e8ne sur les divers navigateurs  *\/||  display: -webkit-box;||  display: -webkit-flex;||  display: -moz-box;||  display: -ms-flexbox;||  -webkit-box-orient: vertical;||  -webkit-box-direction: normal;||  -webkit-flex-direction: column;||     -moz-box-orient: vertical;||     -moz-box-direction: normal;||      -ms-flex-direction: column;||  -webkit-box-pack: center;||  -webkit-justify-content: center;||     -moz-box-pack: center;||      -ms-flex-pack: center;||}&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;&#8211;et_global_body_font|300|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;18px&#8221; text_orientation=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>&#8230;where<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/barretts-picto2-1.png&#8221; title_text=&#8221;barretts-picto2&#8243; show_bottom_space=&#8221;off&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;80%&#8221; custom_padding=&#8221;||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;&#8211;et_global_body_font|300|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;18px&#8221; text_orientation=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>4 out of 5 patient die within 5 years of their diagnosis<sup>3<\/sup><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; custom_padding=&#8221;40px|40px|40px|40px|false|true&#8221; custom_css_main_element=&#8221;min-height:250px;  display: flex;||  flex-direction: column;||  justify-content: center;||||\/* Et les d\u00e9clinaisons avec pr\u00e9fixes pour obtenir un r\u00e9sultat homog\u00e8ne sur les divers navigateurs  *\/||  display: -webkit-box;||  display: -webkit-flex;||  display: -moz-box;||  display: -ms-flexbox;||  -webkit-box-orient: vertical;||  -webkit-box-direction: normal;||  -webkit-flex-direction: column;||     -moz-box-orient: vertical;||     -moz-box-direction: normal;||      -ms-flex-direction: column;||  -webkit-box-pack: center;||  -webkit-justify-content: center;||     -moz-box-pack: center;||      -ms-flex-pack: center;||}&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;&#8211;et_global_body_font|300|||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;18px&#8221; text_orientation=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]1 in 4 cases of EAC is diagnosed within 1 year of normal index endoscopy in patients with BE<sup>4<\/sup>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/barretts-picto3-1.png&#8221; title_text=&#8221;barretts-picto3&#8243; align=&#8221;center&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; width=&#8221;70%&#8221; custom_padding=&#8221;||20px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;centered-text&#8221; module_id=&#8221;centered-text&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||0px||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Based on the growing prevalence of BE and EAC among patients, it is obvious that inadequate surveillance of the esophagus with standard biopsy techniques leads to missed diagnoses of dysplasia and EAC altogether, casting doubt on the role of surveillance endoscopy as it is today.<span style=\"font-size: 13.3333px;\"><sup>5<\/sup><\/span><\/p>\n<p>The Seattle Protocol, or gold standard for index endoscopy procedures, calls for 4-quadrant biopsies every 1 to 2 centimeters. Even if adhered to, the Seattle Protocol<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>proves to have lower detection rates of dysplasia due to the irregularity and complexity of esophageal tissue, suggesting that this systematic approach alone to identifying random islands of dysplasia is insufficient.<span style=\"font-size: 13.3333px;\"><sup>5<\/sup><\/span><\/p>\n<p>With Cellvizio<span><sup>\u00ae<\/sup><\/span> as an adjunct to Seattle protocol, physicians have clear, minimally invasive visualization of the esophagus at the cellular level to obtain a comprehensive assessment of the extent of disease and make real-time therapeutic decisions.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; 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width_tablet=&#8221;&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;30px|30px|30px|30px|true|true&#8221; custom_padding_tablet=&#8221;30px|30px|30px|30px|true|true&#8221; custom_padding_phone=&#8221;55px|0px|0px|0px|false|true&#8221; custom_css_main_element=&#8221; &#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||0px||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;7px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;94px&#8221; custom_margin=&#8221;||10px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; header_2_text_color=&#8221;#FAFAFA&#8221; header_2_font_size=&#8221;40px&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||||false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Cellvizio<sup>\u00ae<\/sup> Clinical Value<\/h2>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; border_radii=&#8221;on|30px|30px|30px|30px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;3_5,2_5&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;4&#8243; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width_tablet=&#8221;&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px|30px|30px|30px|false|true&#8221; custom_padding_tablet=&#8221;0px|30px|30px|30px|false|true&#8221; custom_padding_phone=&#8221;0px|0px|30px|0px|false|true&#8221; custom_css_main_element=&#8221; align-items:center;&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Cellvizio<span><sup>\u00ae<\/sup><\/span> is powered by a technology known as <a href=\"https:\/\/www.maunakeatech.com\/int\/physicians\/11-cellvizio-system\" target=\"_blank\" rel=\"noopener\">probe-based confocal laser endomicroscopy<\/a>, or pCLE, which allows for visibility of cell architecture at the microscopic level. Compared to the standard, random biopsy protocol alone, the addition of Cellvizio<span><sup>\u00ae<\/sup><\/span> as an adjunct technology <b>doubles the detection rate of Barrett&#8217;s Esophagus<\/b><sup>6<\/sup>, where 1.7 times more lesions were detected with Cellvizio<span><sup>\u00ae<\/sup><\/span> and WLE when compared to WLE and NBI alone<sup>7,8<\/sup>. When compared to WLE random biopsies, Cellvizio<span><sup>\u00ae<\/sup><\/span> provides a<span> <\/span><b>significantly higher diagnostic yield and accuracy<\/b><span> <\/span>with reduced sampling error.<sup>5,7<\/sup><\/p>\n<p>Cellvizio<span><sup>\u00ae<\/sup><\/span> advanced imaging and its easy integration into existing workflows allows physicians to better target biopsies within focused areas of concern, augmenting conventional technologies and techniques, and improving the ability to detect and monitor cellular changes.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; border_radii=&#8221;on|30px|30px|30px|30px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/barretts-esophagus.jpeg&#8221; title_text=&#8221;barrett&#8217;s-esophagus&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_css_free_form=&#8221;\/* Hide image titles on hover *\/||img {||pointer-events:none;||}&#8221; border_radii=&#8221;on|30px|30px|30px|30px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_6,1_6,1_6,1_2&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;40px||40px||true|false&#8221; custom_margin_tablet=&#8221;40px||40px||true|false&#8221; custom_margin_phone=&#8221;0px||0px||true|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_6&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;9&#8243; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x69;||divi||400&#8243; icon_color=&#8221;#ff6720&#8243; image_icon_width=&#8221;45px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; text_orientation=&#8221;center&#8221; background_layout=&#8221;dark&#8221; min_height=&#8221;206px&#8221; custom_padding=&#8221;40px||40px||true|false&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>studies<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_6&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;688&#8243; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf183;||fa||900&#8243; icon_color=&#8221;#ff6720&#8243; image_icon_width=&#8221;45px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; text_orientation=&#8221;center&#8221; background_layout=&#8221;dark&#8221; min_height=&#8221;206px&#8221; custom_padding=&#8221;40px||40px||true|false&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>patients<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_6&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;1,299&#8243; image=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/barretts-picto1.png&#8221; image_icon_width=&#8221;45px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; text_orientation=&#8221;center&#8221; background_layout=&#8221;dark&#8221; min_height=&#8221;206px&#8221; custom_padding=&#8221;40px||40px||true|false&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>lesions<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; custom_margin=&#8221;||10px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Compared to random biopsies, the increases in the per patient pooled detection rate of neoplasia with pCLE were as follows:<\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/barretts-4-1.png&#8221; title_text=&#8221;barretts-4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;20px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; background_color=&#8221;#092840&#8243; min_height=&#8221;206px&#8221; min_height_tablet=&#8221;206px&#8221; min_height_phone=&#8221;auto&#8221; min_height_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;12%|30px||30px|false|true&#8221; custom_padding_tablet=&#8221;12%|30px||30px|false|true&#8221; custom_padding_phone=&#8221;12%|30px|12%|30px|true|true&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>assessed the benefits of pCLE as an adjunct to random 4-quadrant biopsies in the surveillance of patients with BE for dysplasia and early EAC detection:<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; module_class=&#8221;centrer-vertical&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/Barretts-Sens-Spec-NPV.png&#8221; title_text=&#8221;Barretts &#8211; Sens Spec NPV&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_css_free_form=&#8221;\/* Hide image titles on hover *\/||img {||pointer-events:none;||}&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;20px||||false|false&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>For surgeons, this technology has the potential to reduce inappropriate endoluminal therapy for non-neoplastic conditions, thus improving overall procedure-related complications, optimizing surveillance intervals, and limiting histological analysis of insignificant lesions.<sup>12<\/sup> This helps improve diagnostic yield and increase the detection of dysplastic lesions from 34% to 68%.<span><sup>7<\/sup><\/span><\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/www.maunakeatech.com\/int\/gi-publication\/&#8221; 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_module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;18px&#8221; background_color=&#8221;#fafafa&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;-2rem||0px|-35px|false|false&#8221; custom_padding=&#8221;124px|50px|30px|50px|false|true&#8221; border_radii=&#8221;off|30px|30px||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\"><span>Cellvizio<sup>\u00ae <\/sup><\/span>makes it possible for us to: rule-in or rule-out the presence of pre-cancerous cells (&#8230;) perform improved surgical intervention (&#8230;) monitor for the presence of cancerous cells after the procedure.<\/p>\n<p>[\/et_pb_text][et_pb_blurb title=&#8221;Dr. J. Burnette, Piedmont Macon North Hospital&#8221; icon_alignment=&#8221;left&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h6&#8243; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#41B6E6&#8243; background_color=&#8221;#fafafa&#8221; custom_margin=&#8221;|||-35px||&#8221; custom_padding=&#8221;|48px|110px|48px|false|true&#8221; hover_enabled=&#8221;0&#8243; custom_css_blurb_image=&#8221;float:left;||margin-right:20px;&#8221; border_radii=&#8221;off|||30px|30px&#8221; border_radii_image=&#8221;on|30px|30px|30px|30px&#8221; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=&#8221;off|on|on&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_video src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/07\/Dr_Burnette_Clinical_720p-2-1.mp4&#8243; image_src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/08\/GERD-barrets-video.jpg&#8221; play_icon_color=&#8221;#071621&#8243; font_icon=&#8221;&#xf144;||fa||900&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|-2px||||&#8221; custom_padding=&#8221;|4px||||&#8221; border_radii=&#8221;on|35px|35px|35px|35px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; play_icon_color__hover_enabled=&#8221;on|hover&#8221; play_icon_color__hover=&#8221;#FFFFFF&#8221;][\/et_pb_video][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_testimonial author=&#8221;Dr. J. Burnette, Coliseum Northside Hospital&#8221; quote_icon=&#8221;off&#8221; disabled_on=&#8221;off|on|on&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; author_text_color=&#8221;#41B6E6&#8243; border_radii=&#8221;on|30px|30px|30px|30px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\"><span>Cellvizio<sup>\u00ae <\/sup><\/span>makes it possible for us to: rule-in or rule-out the presence of pre-cancerous cells (&#8230;) perform improved surgical intervention (&#8230;) monitor for the presence of cancerous cells after the procedure.<\/p>\n<p>[\/et_pb_testimonial][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; z_index=&#8221;0&#8243; custom_padding=&#8221;80px||280px||false|false&#8221; custom_padding_tablet=&#8221;80px||280px||false|false&#8221; 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global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;7px&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;94px&#8221; custom_margin=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#D6D6D6&#8243; header_3_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Cellvizio<sup>\u00ae<\/sup> is part of routine clinical practice<\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>See how Dr. Joseph Burnette, a general surgeon with special interest in reflux uses Cellvizio<sup>\u00ae <\/sup>on all his chronic reflux patients.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; border_radii=&#8221;on|30px|30px|30px|30px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_video src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/Dr_Burnette_Clinical_1080p-1.mp4&#8243; image_src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/img-video1.png&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; custom_padding=&#8221;0px||140px||false|false&#8221; custom_padding_tablet=&#8221;0px||140px||false|false&#8221; custom_padding_phone=&#8221;0px||60px||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; width=&#8221;40%&#8221; width_tablet=&#8221;40%&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;-220px||||false|false&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/logo-1.jpg&#8221; title_text=&#8221;logo&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;18%&#8221; width_tablet=&#8221;18%&#8221; width_phone=&#8221;40%&#8221; width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||20px||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; border_radii=&#8221;on|80px|80px|80px|80px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; width=&#8221;40%&#8221; width_tablet=&#8221;40%&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;-110px||||false|false&#8221; custom_padding=&#8221;80px||70px||false|false&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;18px&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; text_orientation=&#8221;center&#8221; min_height=&#8221;88.2px&#8221; custom_padding=&#8221;7px|50px||50px|false|true&#8221; border_radii=&#8221;off|30px|30px||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Cellvizio<sup>\u00ae<\/sup> adds 3-5 minutes, while more than doubling detection of Barrett&#8217;s Esophagus vs. conventional biopsies.<\/p>\n<p>[\/et_pb_text][et_pb_blurb title=&#8221;Dr. A. McNair Jr.&#8221; icon_alignment=&#8221;left&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h6&#8243; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_color=&#8221;#41B6E6&#8243; background_color=&#8221;RGBA(255,255,255,0)&#8221; text_orientation=&#8221;center&#8221; custom_margin=&#8221;30px||||false|false&#8221; border_radii=&#8221;off|||30px|30px&#8221; border_radii_image=&#8221;on|30px|30px|30px|30px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>New Gulf Coast Surgery Center<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#071621&#8243; background_image=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/AdobeStock_834769802_Preview-2.jpg&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;7px&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;94px&#8221; custom_margin=&#8221;||0px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; header_2_text_color=&#8221;#FAFAFA&#8221; header_2_font_size=&#8221;40px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Patient Management<\/h2>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_5,3_5&#8243; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; width_tablet=&#8221;&#8221; width_phone=&#8221;90%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;20px||||false|false&#8221; custom_padding=&#8221;50px|40px|50px|40px|true|true&#8221; custom_padding_tablet=&#8221;50px|40px|50px|40px|true|true&#8221; custom_padding_phone=&#8221;50px|30px|50px|30px|true|true&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; module_class=&#8221;centrer-vertical&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/patient-management.png&#8221; title_text=&#8221;patient management&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_css_free_form=&#8221;\/* Hide image titles on hover *\/||img {||pointer-events:none;||}&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Cellvizio<sup>\u00ae <\/sup>leads to better informed patient management by providing additional advanced imaging, enabling real-time tissue assessment and early detection. Physicians are able<span> <\/span><b>to rule-in or rule-out intestinal metaplasia<\/b><span> <\/span>in the presence of GERD symptoms<sup>9<\/sup>, allowing for earlier detection of BE<sup>6<\/sup> and the monitoring of such disease.<sup>7,8<\/sup><\/p>\n<p>Physicians also are able to define the location and lateral extent of neoplasia inducing clinical intervention<sup>10<\/sup>, as well as differentiate lesions that are not amenable to EMR and determine the margins of a lesion before endoscopic resection<sup>12<\/sup>. Therefore, pCLE can lead to positive redirection of therapy.<sup>11<\/sup><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#071621&#8243; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||0px||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;7px&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;94px&#8221; custom_margin=&#8221;||0px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; header_2_text_align=&#8221;center&#8221; header_2_text_color=&#8221;#FAFAFA&#8221; header_2_font_size=&#8221;40px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2 style=\"text-align: left;\">Economic Benefit<\/h2>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; width=&#8221;60%&#8221; width_tablet=&#8221;60%&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;20px||||false|false&#8221; custom_padding=&#8221;1px|5px|1px|5px|true|true&#8221; custom_padding_tablet=&#8221;50px|40px|50px|40px|true|true&#8221; custom_padding_phone=&#8221;7px|4px|7px|4px|true|true&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; module_class=&#8221;centrer-vertical&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/11\/EP-Website-Graphic-Update-112024.png&#8221; title_text=&#8221;BE Chart Graphic&#8221; align=&#8221;center&#8221; align_tablet=&#8221;&#8221; align_phone=&#8221;center&#8221; align_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_margin=&#8221;|196px||-18px||&#8221; custom_css_free_form=&#8221;\/* Hide image titles on hover *\/||img {||pointer-events:none;||}&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;60%&#8221; width_tablet=&#8221;60%&#8221; width_phone=&#8221;80%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;20px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_font_size=&#8221;18px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>According to data presented at DDW 2023, \u201cthe use of Cellvizio<span><sup>\u00ae<\/sup><\/span> is associated with lower health services utilization of endoscopy, anesthesia, biopsy, ablation and higher patient satisfaction.\u201d<sup>13<\/sup><\/p>\n<p>Cellvizio<span><sup>\u00ae<\/sup><\/span> enables physicians to assess areas of concern and target biopsies for increased diagnostic yield, optimizing utilization of health service resources and reducing overall number of unnecessary endoscopy procedures required for diagnosis and treatment.<sup>13<\/sup><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#071621&#8243; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;7px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;94px&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;||0px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text disabled_on=&#8221;on|off|off&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FAFAFA&#8221; header_2_font_size=&#8221;40px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Tissue characterization using Cellvizio<sup>\u00ae<\/sup> Gastroflex UHD miniprobe<\/h2>\n<p>[\/et_pb_text][et_pb_text disabled_on=&#8221;off|on|on&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FAFAFA&#8221; header_2_font_size=&#8221;40px&#8221; header_3_text_color=&#8221;#FAFAFA&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Tissue characterization<\/h3>\n<h3>using Cellvizio<sup>\u00ae <\/sup>Gastroflex<\/h3>\n<h3>UHD miniprobe<\/h3>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; width_tablet=&#8221;&#8221; width_phone=&#8221;90%&#8221; width_last_edited=&#8221;on|phone&#8221; max_width=&#8221;1200px&#8221; custom_margin=&#8221;40px||||false|false&#8221; custom_padding=&#8221;50px|70px|50px|70px|true|true&#8221; custom_padding_tablet=&#8221;50px|70px|50px|70px|true|true&#8221; custom_padding_phone=&#8221;50px|30px|50px|30px|true|true&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||15px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Squamous Epithelium<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;4px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;60px&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_css_main_element=&#8221;margin-left: auto;||margin-right: auto;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_orientation=&#8221;center&#8221; min_height=&#8221;130px&#8221; min_height_tablet=&#8221;130px&#8221; min_height_phone=&#8221;130px&#8221; min_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Criteria: squamous epithelium with flat and scale-like cells, intrapapillary loops<\/p>\n<p>[\/et_pb_text][et_pb_video src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/squamus-epithelium.mp4&#8243; image_src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/squamous-epithelium.png&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;50px||50px||false|false&#8221; custom_margin_tablet=&#8221;50px||50px||false|false&#8221; custom_margin_phone=&#8221;||30px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_video][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||15px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Intestinal Metaplasia<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;4px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;60px&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_css_main_element=&#8221;margin-left: auto;||margin-right: auto;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_orientation=&#8221;center&#8221; min_height=&#8221;130px&#8221; min_height_tablet=&#8221;130px&#8221; min_height_phone=&#8221;130px&#8221; min_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Criteria: regular columnar-lined epithelium, dark mucin in goblet cells easily identified, equidistant and regular cells, glands equal in size and shape<\/p>\n<p>[\/et_pb_text][et_pb_video src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/intestinal-metapliasia.mp4&#8243; image_src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/intestinal-metapliasia.png&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;50px||||false|false&#8221; custom_margin_tablet=&#8221;50px||||false|false&#8221; custom_margin_phone=&#8221;25px||30px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_video][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_3_font=&#8221;&#8211;et_global_heading_font|&#8211;et_global_heading_font_weight|||||||&#8221; header_3_text_align=&#8221;center&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||15px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Adenocarcinoma<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#FF6720&#8243; divider_weight=&#8221;4px&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; width=&#8221;60px&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_css_main_element=&#8221;margin-left: auto;||margin-right: auto;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FAFAFA&#8221; text_orientation=&#8221;center&#8221; min_height=&#8221;130px&#8221; min_height_tablet=&#8221;130px&#8221; min_height_phone=&#8221;130px&#8221; min_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Criteria: epithelial surface appearing saw-toothed, non equidistant glands, glands unequal in size and shape, pleomorphic and enlarged cells<\/p>\n<p>[\/et_pb_text][et_pb_video src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/Adenocarcinoma.mp4&#8243; image_src=&#8221;https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2024\/06\/Adenocarcinoma.png&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;50px||||false|false&#8221; custom_margin_tablet=&#8221;50px||||false|false&#8221; custom_margin_phone=&#8221;40px||||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; border_radii=&#8221;on|20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#092840&#8243; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;30px||30px||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_toggle title=&#8221;References &#038; disclaimers&#8221; open_toggle_text_color=&#8221;#FFFFFF&#8221; open_toggle_background_color=&#8221;#071621&#8243; closed_toggle_text_color=&#8221;#FFFFFF&#8221; closed_toggle_background_color=&#8221;#071621&#8243; icon_color=&#8221;#FFFFFF&#8221; toggle_icon=&#8221;&#x33;||divi||400&#8243; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;36px&#8221; open_icon_color=&#8221;#FFFFFF&#8221; open_toggle_icon=&#8221;&#x32;||divi||400&#8243; open_use_icon_font_size=&#8221;on&#8221; open_icon_font_size=&#8221;36px&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;|700|||||||&#8221; title_font_size=&#8221;18px&#8221; closed_title_font=&#8221;|600|||||||&#8221; body_text_color=&#8221;#FFFFFF&#8221; body_font_size=&#8221;14px&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;30px|40px|30px|40px|true|true&#8221; custom_css_free_form=&#8221;selector .et_pb_toggle_content li {||  padding-bottom:8px;||}||selector .et_pb_toggle_content li:marker {||  font-weight:700;||}&#8221; border_radii=&#8221;on|15px|15px|15px|15px&#8221; border_width_all=&#8221;0px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ol>\n<li><span>Bhardwaj A. et al. Barrett\u2019s Esophagus: Emerging Knowledge and Management Strategies. Pathology<\/span><span> Research International, 2012. doi: 10.1155\/2012\/814146.<\/span><\/li>\n<li><span><\/span><span>Chai J. et al. Esophageal malignancy: A growing concern, World Journal of Gastroenterology, 2012. doi: 10.3748\/wjg.v18.i45.6521.<\/span><\/li>\n<li><span>Desai M. et al. Prevalence of HGD and adenocarcinoma on index endoscopy in BE, Gastrointest Endosc, 2018. doi: 10.1016\/j.gie.2018.09.041.<\/span><\/li>\n<li><span>Visrodia K. et al. Magnitude of Missed Esophageal Adenocarcinoma After Barrett\u2019s Esophagus Diagnosis: A Systematic Review and Meta-analysis. Gastroenterology, 2016. doi: 10.1053\/j.gastro.2015.11.040.<\/span><\/li>\n<li><span>DeMeester S. et al. High definition probe-based confocal laser endomicroscopy review and meta-analysis for neoplasia detection in Barrett&#8217;s esophagus. Techniques and Innovations in Gastrointestinal Endoscopy, 2022. doi: 10.1016\/j.tige.2022.06.001.<\/span><\/li>\n<li><span>Richardson C. et al. Real-time diagnosis of Barrett\u2019s Esophagus: a prospective, multicenter study comparing confocal laser endomicroscopy with conventional histology for the identification of intestinal metaplasia in new users, Surgical Endoscopy, 2018. doi: 10.1007\/s00464-018-6420-9.<\/span><\/li>\n<li><span>Sharma P. et al. Real-time increased detection of Neoplastic tissue in Barrett\u2019s Esophagus with pCLE; Final results of a multi-center prospective international randomized controlled trial, Gastrointest Endosc, 2011. doi: 10.1016\/j.gie.2011.04.004.<\/span><\/li>\n<li><span>Canto M. et al. In vivo endomicroscopy improves detection of Barrett\u2019s Esophagus related neoplasia: a multicenter international randomized controlled trial, GIE, 2013. doi: 10.1016\/j.gie.2013.09.020.<\/span><\/li>\n<li><span>Kiesslich R. et al. In vivo histology of Barrett\u2019s Esophagus and Associated Neoplasia by CLE, Clinical Gastro and Hepatology, 2006.<\/span><\/li>\n<li><span>Wang K. et al. Use of probe-based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence. UEGW Journal, 2015. doi: 10.1177\/2050640614566066.<\/span><\/li>\n<li><span>Caillol et al. Probe confocal laser endomicroscopy in the therapeutic endoscopic management of Barrett\u2019s dysplasia. Annals of Gastroenterology, 2017. doi: 10.20524\/aog.2017.0138.<\/span><\/li>\n<li><span>Al-Mansour. et al. SAGES TAVAC safety and efficacy analysis confocal laser endomicroscopy. Surg Endosc, 2020. doi: 10.1007\/s00464-020-07607-3. <\/span><\/li>\n<li><span>Randhawa N, et al. A comparison of patient satisfaction and healthcare resource use in patients with Barrett&#8217;s Esophagus using CLE based approach versus standard of care. DDW 2023 Poster. https:\/\/eposters.ddw.org\/ddw\/2023\/ddw-2023\/377845\/navkiran.randhawa.a.comparison.of.patient.satisfaction.and.healthcare.resource.html<\/span><\/li>\n<\/ol>\n<p><span><\/span><\/p>\n<p><span>Cellvizio<sup>\u00ae<\/sup> I.V.E. with Confocal Miniprobes\u2122 are regulated Medical Devices, CE marked (CE 0459) (Class IIa &#8211; NB : G-MED) and FDA cleared. Cellvizio<sup>\u00ae<\/sup> is a registered trademark and Confocal Miniprobe\u2122 is a trademark of Mauna Kea Technologies. Cellvizio<sup>\u00ae<\/sup> I.V.E. with Confocal Miniprobes\u2122 is a confocal laser system with fiber optic probes that is intended to allow imaging of the internal microstructure of tissues including, but not limited to, the identification of cells and vessels and their organization or architecture. Once connected to the Cellvizio<sup>\u00ae<\/sup> I.V.E.: The GastroFlex\u2122 UHD and ColoFlex\u2122 UHD Confocal Miniprobes\u2122 are intended to allow imaging of anatomical tracts, i.e., gastrointestinal systems, accessed by an endoscope or endoscopic accessories. Please consult labels and instructions for use. These statements and the associated reference to specific clinical studies, are not intended to represent claims of safety or effectiveness for detecting or treating any specific condition or disease state. Rather this information is intended to provide useful reference to selected published literature describing physician experiences with the associated clinical uses. Any diagnostic assessment should always be made by the attending physician, based on the evaluation of all sources of clinical, endoscopic and other relevant information. These statements have not been reviewed, cleared, or approved by the U.S. FDA. The use of this medical device is exclusively reserved for health professionals. Product availability cannot be guaranteed in all countries. For further information, please contact your local sales representative.<\/span><\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;news-events&#8221; module_id=&#8221;news-events&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(255,255,255,0)&#8221; da_disable_devices=&#8221;off|off|off&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; pac_dcm_carousel_specific_module_num=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_text_color=&#8221;#41B6E6&#8243; text_font_size=&#8221;22px&#8221; custom_margin=&#8221;||20px||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>News<\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|&#8211;et_global_heading_font_weight|||||||&#8221; header_2_text_color=&#8221;#FAFAFA&#8221; header_2_font_size=&#8221;40px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2 class=\"section__title section__title--small\">YOU MIGHT 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the progression of GERD to Barrett\u2019s Esophagus (BE) over time using proprietary advanced imaging technology.Esophageal cancer is the fastest growing cancer\u00b2&#8230;&#8230;where4 out of 5 patient die within 5 years [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":8466,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1183","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Barrett\u2019s Esophagus - Mauna Kea Technologies<\/title>\n<meta name=\"description\" content=\"Cellvizio\u00ae is the real-time in vivo cellular imaging platform that is an adjunct to the standard of care and enables physicians to detect and monitor the progression of GERD to BE over time using 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