{"id":18364,"date":"2026-11-04T17:45:00","date_gmt":"2026-11-04T16:45:00","guid":{"rendered":"https:\/\/www.maunakeatech.com\/?p=18364"},"modified":"2026-11-04T19:50:18","modified_gmt":"2026-11-04T18:50:18","slug":"mauna-kea-technologies-annonce-le-lancement-de-celltolerance-a-la-cleveland-clinic-abu-dhabi-premier-hopital-de-la-region-du-moyen-orient-et-afrique-du-nord-mena-a-proposer-le-programme","status":"publish","type":"post","link":"https:\/\/www.maunakeatech.com\/fr\/actualites\/mauna-kea-technologies-annonce-le-lancement-de-celltolerance-a-la-cleveland-clinic-abu-dhabi-premier-hopital-de-la-region-du-moyen-orient-et-afrique-du-nord-mena-a-proposer-le-programme\/","title":{"rendered":"Mauna Kea Technologies annonce le lancement de CellTolerance\u00ae \u00e0 la Cleveland Clinic Abu Dhabi, premier h\u00f4pital de la r\u00e9gion du Moyen-Orient et Afrique du Nord (MENA) \u00e0 proposer le programme\u00a0"},"content":{"rendered":"\n<p class=\"has-text-align-center wp-block-paragraph\"><strong><em>La Cleveland Clinic Abu Dhabi est class\u00e9e n\u00b01 en gastro-ent\u00e9rologie au Moyen-Orient1<sup>&nbsp;<\/sup><\/em><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><strong><em>Un d\u00e9ploiement commercial tr\u00e8s prometteur qui ouvre l\u2019acc\u00e8s \u00e0 l\u2019une des r\u00e9gions affichant la plus forte pr\u00e9valence du syndrome de l\u2019intestin irritable (SII) au monde (~27% en moyenne r\u00e9gionale<sup>2<\/sup><\/em><\/strong> <strong>contre 9,2% \u00e0 l\u2019\u00e9chelle mondiale<em><sup>3<\/sup>)&nbsp;<\/em><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><strong><em>CellTolerance permet aux m\u00e9decins d\u2019identifier des r\u00e9actions alimentaires chez 70% des patients atteints du SII pr\u00e9sentant des tests d\u2019allergie standards n\u00e9gatifs<sup>4<\/sup>, et de les orienter vers un r\u00e9gime cibl\u00e9 sans \u00e9victions alimentaires inutiles&nbsp;<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Paris et Boston, le 4 novembre 2026 \u2013 17h45 CET \u2013 Mauna Kea Technologies (Euronext Growth : ALMKT)<\/strong>, inventeur de Cellvizio<sup>\u00ae<\/sup>, la plateforme multidisciplinaire d\u2019endomicroscopie confocale laser par sonde et par aiguille (p\/nCLE), annonce aujourd\u2019hui le lancement clinique de CellTolerance<sup>\u00ae<\/sup> au sein de la Cleveland Clinic Abu Dhabi, \u00e9tablissement du r\u00e9seau de sant\u00e9 M42 d\u00e9sign\u00e9 meilleur h\u00f4pital sp\u00e9cialis\u00e9 en gastro-ent\u00e9rologie au Moyen-Orient par <em>Newsweek<\/em> (voir <a href=\"https:\/\/www.clevelandclinicabudhabi.ae\/en\/media-center\/news\/ccad-offers-advanced-food-intolerance-test-for-the-first-time-in-the-middle-east-and-north-africa\">le communiqu\u00e9 de la Cleveland Clinic Abu Dhabi<\/a>). Apr\u00e8s l\u2019autorisation de mise sur le march\u00e9 accord\u00e9e aux \u00c9mirats arabes unis par l\u2019<em>Emirates Drug Establishment<\/em> en mai 2026 ainsi que l\u2019approbation du <em>Department of Health \u2013 Abu Dhabi<\/em>, le <em>Digestive Disease Institute<\/em> de l\u2019h\u00f4pital devient le premier centre de la r\u00e9gion Moyen-Orient et Afrique du Nord (MENA) \u00e0 proposer le programme CellTolerance<sup>\u00ae<\/sup> aux patients souffrant d\u2019un syndrome de l\u2019intestin irritable (SII) possiblement li\u00e9 \u00e0 l\u2019alimentation.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Le Moyen-Orient figure parmi les r\u00e9gions les plus touch\u00e9es au monde par le SII. Une revue syst\u00e9matique publi\u00e9e en 2024 et portant sur 52 \u00e9tudes (51 683 participants r\u00e9partis dans sept pays arabes) montre que le SII affecte en moyenne pr\u00e8s de 27% de la population2, contre une pr\u00e9valence mondiale estim\u00e9e \u00e0 9,2% selon une m\u00e9ta-analyse de 2020 bas\u00e9e sur les crit\u00e8res de Rome III<sup>3<\/sup>. Dans une \u00e9tude publi\u00e9e dans l\u2019<em>American Journal of Gastroenterology<\/em>, 84% des patients atteints du SII rapportent des sympt\u00f4mes d\u00e9clench\u00e9s par au moins un aliment<sup>5<\/sup>. Pourtant, le bilan diagnostique conventionnel \u00e9choue le plus souvent \u00e0 en identifier l\u2019origine : les tests sanguins et cutan\u00e9s standards ne d\u00e9tectent que les allergies alimentaires classiques m\u00e9di\u00e9es par les IgE,\u00a0laissant de nombreuses r\u00e9actions non diagnostiqu\u00e9es. Dans une \u00e9tude prospective publi\u00e9e dans <em>Gastroenterology<\/em>, 70% des patients atteints du SII dont les tests sanguins d\u2019IgE et les prick-tests cutan\u00e9s \u00e9taient n\u00e9gatifs ont pr\u00e9sent\u00e9 une r\u00e9action imm\u00e9diate \u00e0 au moins un composant alimentaire courant sous endomicroscopie confocale laser<sup>4<\/sup>. Faute d\u2019outil permettant de visualiser ces r\u00e9actions, les patients sont souvent contraints \u00e0 des mois, voire des ann\u00e9es, de r\u00e9gimes d\u2019\u00e9viction par t\u00e2tonnement.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CellTolerance<sup>\u00ae<\/sup> a \u00e9t\u00e9 con\u00e7u pour substituer \u00e0 ces t\u00e2tonnements une preuve visuelle directe. R\u00e9alis\u00e9 sous s\u00e9dation au cours d\u2019une endoscopie digestive haute standard d\u2019une dur\u00e9e inf\u00e9rieure \u00e0 30 minutes, l\u2019examen consiste \u00e0 appliquer des extraits alimentaires liquides rigoureusement s\u00e9lectionn\u00e9s sur la paroi du duod\u00e9num, tandis que le m\u00e9decin observe en temps r\u00e9el la r\u00e9ponse de la muqueuse gr\u00e2ce \u00e0 l\u2019endomicroscopie confocale laser Cellvizio<sup>\u00ae<\/sup>. Des alt\u00e9rations de la barri\u00e8re intestinale, telles que des ruptures de l\u2019\u00e9pith\u00e9lium ou une fuite liquidienne intercellulaire, peuvent appara\u00eetre en quelques minutes. Ces observations apportent aux cliniciens des preuves visuelles propres \u00e0 chaque patient, en compl\u00e9ment des tests conventionnels, afin d\u2019orienter une prise en charge nutritionnelle cibl\u00e9e qui \u00e9vite les restrictions alimentaires inutiles et pr\u00e9serve l\u2019\u00e9quilibre nutritionnel.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Le Dr Sacha Sidani, m\u00e9decin gastro-ent\u00e9rologue au sein du Digestive Disease Institute de la Cleveland Clinic Abu Dhabi<\/strong>, d\u00e9clare : <em>\u00ab De nombreux patients s\u2019entendent dire pendant des ann\u00e9es que leurs sympt\u00f4mes se r\u00e9sument \u00e0 un \u201csimple c\u00f4lon irritable\u201d, passant d\u2019un r\u00e9gime \u00e0 l\u2019autre sans r\u00e9ponse claire. CellTolerance nous permet de visualiser directement, et en temps r\u00e9el, la mani\u00e8re dont l\u2019intestin de chaque patient r\u00e9agit \u00e0 des aliments sp\u00e9cifiques. Des patients viennent consulter \u00e0 la Cleveland Clinic Abu Dhabi depuis toute la r\u00e9gion, et nous anticipons une forte demande de la part de ceux qui vivent avec ces sympt\u00f4mes depuis des ann\u00e9es. Les patients accueillent ce test avec un r\u00e9el enthousiasme et ceux que nous avons pris en charge jusqu\u2019\u00e0 pr\u00e9sent s\u2019en montrent extr\u00eamement satisfaits. Le lancement de CellTolerance au sein de notre \u00e9tablissement, en tant que premier centre d\u2019excellence au Moyen-Orient, illustre notre engagement \u00e0 rendre les soins digestifs les plus avanc\u00e9s accessibles au plus pr\u00e8s des patients. \u00bb&nbsp;<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Sacha Loiseau, Ph.D., Pr\u00e9sident-Directeur G\u00e9n\u00e9ral de Mauna Kea Technologies<\/strong>, ajoute : <em>\u00ab Le lancement de CellTolerance<sup>\u00ae<\/sup> au Moyen-Orient et en Afrique du Nord avec la Cleveland Clinic Abu Dhabi, l\u2019une des institutions m\u00e9dicales les plus respect\u00e9es au monde, constitue une \u00e9tape majeure pour le programme. Il conforte \u00e9galement notre strat\u00e9gie consistant \u00e0 nous associer \u00e0 des centres de renomm\u00e9e mondiale pour acc\u00e9l\u00e9rer l\u2019adoption de notre technologie. La Cleveland Clinic Abu Dhabi rejoint des centres de r\u00e9f\u00e9rence de premier plan tels que l\u2019Universit\u00e9 de Stanford et le Hoag Memorial Hospital aux \u00c9tats-Unis, ainsi que l\u2019Universit\u00e9 de Mayence et le Klinikum Bamberg en Allemagne, o\u00f9 l\u2019approche CellTolerance a \u00e9t\u00e9 d\u00e9velopp\u00e9e. La pr\u00e9valence du SII dans cette r\u00e9gion figure parmi les plus \u00e9lev\u00e9es au monde, et plus de huit patients sur dix associent leurs sympt\u00f4mes \u00e0 leur alimentation. Le besoin m\u00e9dical est consid\u00e9rable, et les patients du Golfe et de l\u2019ensemble de la r\u00e9gion MENA b\u00e9n\u00e9ficient d\u00e9sormais d\u2019un examen qui remplace les r\u00e9gimes par t\u00e2tonnement par des preuves cliniques tangibles. \u00bb&nbsp;<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>1<\/sup> https:\/\/www.clevelandclinicabudhabi.ae\/en\/media-center\/news\/ccad-ranks-first-in-the-uae-across-five-specialties&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>2 <\/sup>Almansour O. Prevalence of Irritable Bowel Syndrome (IBS) in the Arab World: A Systematic Review. Cureus. 2024 Jul 26;16(7):e65421. doi:10.7759\/cureus.65421&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>3<\/sup> Oka P, et al. Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2020;5:908\u201317&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>4<\/sup> Fritscher-Ravens A, Pflaum T, M\u00f6singer M, et al. Many patients with irritable bowel syndrome have atypical food allergies not associated with immunoglobulin E. Gastroenterology. 2019;157(1):109\u2013118.e5. doi:10.1053\/j.gastro.2019.03.046&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>5<\/sup> B\u00f6hn L, St\u00f6rsrud S, T\u00f6rnblom H, Bengtsson U, Simr\u00e9n M. Self-reported food-related gastrointestinal symptoms in IBS are common and associated with more severe symptoms and reduced quality of life. Am J Gastroenterol. 2013;108(5):634\u201341. doi:10.1038\/ajg.2013.105&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.maunakeatech.com\/wp-content\/uploads\/2026\/11\/CP_ALMKT_Cleveland_2026-11-04_FR.pdf\">VOIR LE COMMUNIQU\u00c9 DE PRESSE<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La Cleveland Clinic Abu Dhabi est class\u00e9e n\u00b01 en gastro-ent\u00e9rologie au Moyen-Orient1&nbsp; Un d\u00e9ploiement commercial tr\u00e8s prometteur qui ouvre l\u2019acc\u00e8s \u00e0 l\u2019une des r\u00e9gions affichant la plus forte pr\u00e9valence du syndrome de l\u2019intestin irritable (SII) au monde (~27% en moyenne r\u00e9gionale2 contre 9,2% \u00e0 l\u2019\u00e9chelle mondiale3)&nbsp; CellTolerance permet aux m\u00e9decins d\u2019identifier des r\u00e9actions alimentaires chez [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":2807,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"off","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[29],"tags":[],"class_list":["post-18364","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - 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