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01/03/2010 - Cellvizio for GI Disease Detection at Georgetown
Doctors at Georgetown University Hospital use Cellvizio, "the world’s smallest flexible microscope to diagnose gastrointestinal and biliary diseases during regular endoscopy procedures so patients can be treated immediately"





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Cellvizio® GI publications
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Download the Cellvizio bibliography in pdf format

Download the DDW 2009 scientific compendium in pdf format

Cellvizio® GI publications

Peer-reviewed Publications

2010
Shahid, M. W., & Wallace, M. B. (2010). Endoscopic imaging for the detection of esophageal dysplasia and carcinoma. Gastrointest Endosc Clin N Am, 20(1), 11–24, v. Notes: PMID:19951791. DOI url
2009
Buchner, A. M., Shahid, M. W., Heckman, M. G., Krishna, M., Ghabril, M., Hasan, M., et al. (2009). Comparison of probe based Confocal Laser Endomicroscopy with Virtual Chromoendoscopy for Classification of Colon Polyps. Gastroenterology, [Epub ahead of print]. Notes: PMID:19909747. DOI url
De Palma, G. - D. (2009). Confocal laser endomicroscopy in the “in vivo” histological diagnosis of the gastrointestinal tract. World J Gastroenterol, 15(46), 5770–5775. Notes: PMID:19998496. DOI pdf
Meining, A. (2009). Confocal endomicroscopy. Gastrointest Endosc Clin N Am, 19(4), 629–635. Notes: PMID:19917468. DOI url
Meining, A., Phillip, V., Gaa, J., Prinz, C., & Schmid, R. M. (2009). Pancreaticoscopy with miniprobe-based confocal laser-scanning microscopy of an intraductal papillary mucinous neoplasm (with video). Gastrointest Endosc, 69(6), 1178–1180. Notes: PMID:19152895. DOI
Monkemuller, K., Neumann, H., & Fry, L. C. (2009). Endoscopic examination of the small bowel: from standard white light to confocal endomicroscopy. Clin Gastroenterol Hepatol, 7(2), e11–2. Notes: PMID:18955164. DOI url
Wallace, M. B. (2009). Advances in imaging and technology of pre-invasive neoplasia: the big (and small) picture. Gastroenterology, 137(5), 1582–1583. Notes: PMID:19781544. DOI url
Wallace, M. B., & Fockens, P. (2009). Probe-based confocal laser endomicroscopy. Gastroenterology, 136(5), 1509–1513. Notes: PMID:19328799. DOI url
Wallace, M. B., Meining, A., Canto, M. I., Fockens, P., Miehlke, S., Roesch, T., et al. (2009). Review article: safety of intravenous fluorescein for confocal laser endomicroscopy in the gastrointestinal tract. Aliment Pharmacol Ther, . Notes: PMID:20002025. DOI url
2008
Becker, V., Vieth, M., Bajbouj, M., Schmid, R. M., & Meining, A. (2008). Confocal laser scanning fluorescence microscopy for in vivo determination of microvessel density in Barrett's esophagus. Endoscopy, 40(11), 888–891. Notes: PMID:19009480. DOI url
Becker, V., von Delius, S., Bajbouj, M., Karagianni, A., Schmid, R. M., & Meining, A. (2008). Intravenous application of fluorescein for confocal laser scanning microscopy: evaluation of contrast dynamics and image quality with increasing injection-to-imaging time. Gastrointest Endosc, 68(2), 319–323. Notes: PMID:18436217. DOI
Hsiung, P. L., Hardy, J., Friedland, S., Soetikno, R., Du, C. B., Wu, A. P., et al. (2008). Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. Nat Med, 14(4), 454–458. Notes: PMID:18345013. DOI
Meining, A., & Wallace, M. B. (2008). Endoscopic imaging of angiogenesis in vivo. Gastroenterology, 134(4), 915–918. Notes: PMID:18395072. DOI
Meining, A., Frimberger, E., Becker, V., Delius, S. V., Weyhern, C. H., Schmid, R. M., et al. (2008). Detection of Cholangiocarcinoma In Vivo Using Miniprobe-Based Confocal Fluorescence Microscopy. Clin Gastroenterol Hepatol, 6(9), 1057–1060. Notes: PMID:18639496. DOI
Pohl, H., Rosch, T., Vieth, M., Koch, M., Becker, V., Anders, M., et al. (2008). Miniprobe confocal laser microscopy for the detection of invisible neoplasia in patients with Barrett's esophagus. Gut, 57(12), 1648–1653. Notes: PMID:18755886. DOI
2007
Becker, V., Vercauteren, T., von Weyern, C. H., Prinz, C., Schmid, R. M., & Meining, A. (2007). High Resolution Miniprobe-based Confocal Microscopy in Combination with Video-mosaicing. Gastrointestinal Endoscopy, 66(5), 1001–1007. Notes: PMID: 17767932. DOI
Meining, A., Bajbouj, M., & Schmid, R. M. (2007). Confocal Fluorescence Microscopy for Detection of Gastric Angiodysplasia. Endoscopy, 39(S 1), E145. Notes: PMID: 17611888. DOI pdf
Meining, A., Bajbouj, M., von Delius, S., & Prinz, C. (2007). Confocal Laser Scanning Microscopy for in vivo Histopathology of the Gastrointestinal Tract. Arab Journal of Gastroenterology, 8(1), 1–4. pdf
Meining, A., Saur, D., Bajbouj, M., Becker, V., Peltier, E., Höfler, H., et al. (2007). In Vivo Histopathology for Detection of Gastrointestinal Neoplasia with a Portable, Confocal Miniprobe: An Examiner Blinded Analysis. Clinical Gastroenterology and Hepatology, 5(11), 1261–1267. Notes: PMID: 17689297. DOI
Meining, A., Schwendy, S. B. V., Schmid, R. M., & Prinz, C. (2007). In Vivo Histopathology of Lymphocytic Colitis. Gastrointestinal Endoscopy, 66(2), 398–400. Notes: PMID: 17521648. DOI
Miehlke, S., Morgner, A., Aust, D., Madisch, A., Vieth, M., & Baretton, G. (2007). Combined use of narrow-band imaging magnification endoscopy and miniprobe confocal laser microscopy in neoplastic Barrett's esophagus. Endoscopy, 39, E316. DOI pdf
Morgner, A., Stolte, M., & Miehlke, S. (2007). Visualization of lymphoepithelial lesions in gastric mucosa-associated lymphoid tissue-type lymphoma by miniprobe confocal laser microscopy. Clin Gastroenterol Hepatol, 5(9), e37. Notes: PMID:17825764. DOI
von Delius, S., Feussner, H., Wilhelm, D., Karagianni, A., Henke, J., Schmid, R. M., et al. (2007). Transgastric In Vivo Histology in the Peritoneal Cavity using Miniprobe-based Confocal Fluorescence Microscopy in an Acute Porcine Model. Endoscopy, 39(5), 407–411. Notes: PMID: 17516346. DOI
Wang, T. D., Friedland, S., Sahbaie, P., Soetikno, R., Hsiung, P. - L., Liu, J. T. C., et al. (2007). Functional Imaging of Colonic Mucosa with a Fibered Confocal Microscope for Real-time In Vivo Pathology. Clinical Gastroenterology and Hepatology, 5(1), 1300–1305. Notes: PMID: 17936692. DOI

Conference Proceedings

2006
Osdoit, A., Genet, M., Perchant, A., Loiseau, S., Abrat, B., & Lacombe, F. (2006). In vivo fibered confocal reflectance imaging: totally non-invasive morphological cellular imaging brought to the endoscopist. In G. J. Tearney, & T. D. Wang (Eds.), Endoscopic Microscopy (Vol. 6082, pp. 608208–608210). San Jose, CA, USA: SPIE. DOI
Viellerobe, B., Osdoit, A., Cave, C., Lacombe, F., Loiseau, S., & Abrat, B. (2006). Mauna Kea Technologies' F400 prototype: a new tool for in vivo microscopic imaging during endoscopy. In G. J. Tearney, & T. D. Wang (Eds.), Endoscopic Microscopy (Vol. 6082, 60820c). SPIE. DOI

Abstracts

2009
Becker, V., Delius, S. von, Voermans, R., Woodward, T., Fockens, P., Wallace, M., et al. (2009). Erste Ergebnisse der konfokalen-Sondenbasierten Lasermikroskopie über eine Punktionsnadel zur Beurteilung der in-vivo Histologie intraabdomineller Organe in einem Schweinemodell. In Z Gastroenterol (Vol. 47, 232). DOI
Becker, V., van den Broek, F., Buchner, A., Delius, S., Decker, E., Wallace, M., et al. (2009). Intravenöse Applikation von Fluorescein im Rahmen der konfokalen Lasermikroskopie – Dosisfindungstudie am Schweinemodell. In Zeitschrift für Gastroenterologie (Vol. 47). DOI url
Becker, V., Wallace, M., Fockens, P., Delius, S. von, Woodward, T., Raimondo, M., et al. (2009). Sondenbasierte konfokale Punktions-Lasermikroskopie (nCLE) zur Beurteilung der in-vivo Histologie intraabdomineller Organe im Schweinemodell. In Zeitschrift für Gastroenterologie (Vol. 47). DOI url
Buchner, A. M., Gomez, V., Gill, K. R., Ghabril, M., Scimeca, D., Shahid, M. W., et al. (2009). The Learning Curve for In Vivo Probe Based Confocal Laser Endomicroscopy (pCLE) for Prediction of Colorectal Neoplasia. In Gastrointestinal Endoscopy (Poster presentation at DDW) (Vol. 69, pp. AB364–AB365). DOI url
Buchner, A. M., Shahid, M. W., van den Broek, F. J., Dekker, E., Gomez, V., Ghabril, M., et al. (2009). Probe Based Confocal Laser Endomicroscopy (pCLE) in Predicting Recurrence of Neoplasia After Endoscopic Mucosal Resection of Colorectal Lesions. In Gastrointestinal Endoscopy (Poster presentation at DDW) (Vol. 69, AB367). DOI url
Chuttani, R. (2009). Digital Cholangioscopy with Narrow Band Imaging and Confocal Microscopy. In DDW (Video forum, oral presentation). Notes: Available online at “The DAVE Project”. url
Coron, E., Mosnier, J. F., Ahluwalia, A., Le Rhun, M., Tarnawski, A. S., Matysiak-Budnik, T., et al. (2009). Colonic Biopsy Specimens Obtained During Confocal Endomicroscopy Are In Vivo Prestained with Fluorescein and Exceptionally Suited for Cellular and Molecular Imaging. In DDW (Poster presentation). url
Dabizzi, E., Manta, R., Bertani, H., Manno, M., Mussetto, A., Trande, P., et al. (2009). In Vivo Histopathology with Portable Confocal Miniprobes Endomicroscopy in the Diagnosis of Celiac Disease (CD). In Gastrointestinal Endoscopy (Poster presentation at DDW) (Vol. 69, AB374). DOI url
Dabizzi, E., Manta, R., Bertani, H., Manno, M., Mussetto, A., Trande, P., et al. (2009). In Vivo Histopathology With Portable Confocal Miniprobes Endomicroscopy In The Diagnosis Of Celiac Disease (CD). In Digestive and Liver Disease (Presented at FISMAD) (Vol. 41, S87). DOI url
Dabizzi, E., Mussetto, A., Manno, M., Bertani, H., Frazzoni, M., Manta, R., et al. (2009). In Vivo Histopathology Of Barrett'S Esophagus (BE) With Portable Confocal Mini-Probes Endomicroscopy. In Digestive and Liver Disease (Presented at FISMAD) (Vol. 41, S80). DOI url
Gomez, V., Buchner, A. M., Dekker, E., van den Broek, F. J., Meining, A., Shahid, M. W., et al. (2009). Interobserver Agreement and Accuracy Among International Experts of Probe-Based Confocal Laser Microscopy (pCLE) in Predicting Colorectal Neoplasia. In DDW (Poster presentation). url
Jamil, L. H., Rahban, S., & Lo, S. K. (2009). Use of Probe Confocal Laser Endomicroscopy for Tumor Margin Identification for Surgical Resection. A Case Report. In ACG. url
Manta, R., Dabizzi, E., Bertani, H., Manno, M., Mussetto, A., Trande, P., et al. (2009). Confocal Endomicroscopy (CEM) With Portable Mini Probes For Characterization Of Polypoid And Non-Polypoid Colorectal Lesions: A New Tool For The Next Generation. In Digestive and Liver Disease (Presented at FISMAD) (Vol. 41, S55). DOI url
Matysiak-Budnik, T., Coron, E., Mosnier, J. - F., Le Rhun, M., Galmiche, J. - P., Ahluwalia, A., et al. (2009). Quantitative In Vivo Assessment of Vascular Permeability in Human Colonic Mucosa Using Confocal Endomicroscopy: Clinical Implications for Colonic Neoplasia. In DDW (Oral presentation). url
Meining, A. (2009). Biliary Imaging. In DDW (Oral presentation). url
Meining, A., Vieth, M., Rosch, T., Miehlke, S., Becker, V., Anders, M., et al. (2009). Probe-Based Confocal Endomicroscopy Is Equivalent to Standard Four-Quadrant-Stepwise Biopsy Technique for Diagnosis of Neoplasia Arising from Barrett's Esophagus. In DDW (Oral presentation). url
Nguyen, V. X., Nguyen, C. C., Leighton, J. A., Pasha, S. F., DePetris, G., Gurudu, S., et al. (2009). Accuracy and Inter-Observer Agreement in Identifying Neoplastic Gastrointestinal Mucosal Pathology By Probe-Based Confocal Laser Endomicroscopy (pCLE). In Gastrointestinal Endoscopy (Poster presentation at DDW) (Vol. 69, AB364). DOI url
Schmidt, C., & Stallmach, A. (2009). Contrast Improvement in Probe-Base Confocal Laser Endomicroscopy (pCLE) By Use of a Low Fluorescein Concentration. In DDW (Poster presentation). url
Shahid, M. W., Buchner, A. M., Hasan, M. K., Gomez, V., & Wallace, M. B. (2009). The Role of Probe-Based Confocal Laser Endomicroscopy (pCLE) in Detection of Dysplasia in Duodenal Polyps. In Gastrointestinal Endoscopy (Poster presentation at DDW) (Vol. 69, AB369). DOI url
Stevens, P. D., Chen, Y. K., Shah, R. J., Chuttani, R., & Pleskow, D. K. (2009). Real-Time Intraductal Confocal Microscopy During ERCP: Feasibility and Technical Considerations. In Gastrointestinal Endoscopy (Poster presentation at DDW) (Vol. 69, AB267). DOI url
Tarnawski, A. S., Coron, E., Mosnier, J. - F., Ahluwalia, A., Le Rhun, M., Galmiche, J. - P., et al. (2009). In-Vivo Detection By Confocal Endomicroscopy of Two Distinct Structural Abnormalities in Angioarchitecture and Increased Vascular Permeability in Colonic Mucosa of Patients with IBD in Remission: Mechanistic Implications. In DDW (Oral presentation). url
van den Broek, F. J., Meining, A., Wallace, M. B., Buchner, A. M., van Eeden, A., van Es, J. A., et al. (2009). Generation of a New Classification Scheme for Probe-Based Confocal Laser Endomicroscopy By International Experts Including Their Interobserver Agreement and Accuracy. In DDW (Poster presentation). url